Animal Nutrition Research

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Sheep and Goat

Kwon, H., T.E. Spencer, F.W. Bazer, and G. Wu. 2003. Developmental changes of amino acids in ovine fetal fluids. Biol. Reprod. 68:1813-1820.

Kwon, H., G. Wu, F.W. Bazer, and T.E. Spencer. 2003. Developmental changes in polyamine levels and synthesis in the ovine conceptus. Biol. Reprod. 69:1626-1634.

Kwon, H., G. Wu, C.J. Meininger, F.W. Bazer, and T.E. Spencer. 2004. Developmental changes in nitric oxide synthesis in the ovine conceptus. Biol. Reprod. 70:679-686.

Kwon, H., S.P. Ford, F.W. Bazer, T.E. Spencer, P.W. Nathanielsz, M.J. Nijland, B.W. Hess, and G. Wu. 2004. Maternal undernutrition reduces concentrations of amino acids and polyamines in ovine maternal and fetal plasma and fetal fluids. Biol. Reprod. 71:901-908.

Wu, G., F.W. Bazer, T.A. Cudd, C.J. Meininger, and T.E. Spencer. 2004. Maternal nutrition and fetal development. J. Nutr. 134:2169-2172.

Fang, Y.Z., S. Yang, and G. Wu. 2005. Homeostasis of free radicals and thiols: nutritional regulation and implications for health and ageing. Res. Adv. Biol. Chem. 3:11-24.

Wu, G., F.W. Bazer, J.M. Wallace, and T.E. Spencer. 2006. Intrauterine growth retardation: Implications for the animal sciences. J. Anim. Sci. 84:2316-2337.

Jobgen, W.S., S.C. Jobgen, H. Li, C.J. Meininger, and G. Wu. 2007. Analysis of nitrite and nitrate in biological samples using high-performance liquid chromatography. J. Chromatogr. B 851:71-82.

Jobgen, W.S., S. P. Ford, S. C. Jobgen, C. P. Feng, B. W. Hess, P. W. Nathanielsz, P. Li, and G. Wu. 2008. Baggs ewes adapt to maternal undernutrition and maintain conceptus growth by maintaining fetal plasma concentrations of amino acids. J. Anim. Sci. 86:820-826.

Gao, H.J., G. Wu, T.E. Spencer, G.A. Johnson, X.L. Li, and F.W. Bazer. 2009. Select nutrients in the ovine uterine lumen: I. Amino acids, glucose and ions in uterine lumenal flushings of cyclic and pregnant ewes. Biol. Reprod. 80:86-93.

Gao, H.J., G. Wu, T.E. Spencer, G.A. Johnson, and F.W. Bazer. 2009. Select nutrients in the ovine uterine lumen: II. Glucose transporters in the uterus and peri-implantation conceptuses. Biol. Reprod. 80:94-104.

Gao, H.J., G. Wu, T.E. Spencer, G.A. Johnson, and F.W. Bazer. 2009. Select nutrients in the ovine uterine lumen: III. Expression of cationic amino acid transporters in ovine uterus and peri-implantation conceptuses. Biol. Reprod. 80:602-609.

Gao, H., G. Wu, T.E. Spencer, G.A. Johnson, and F.W. Bazer. 2009. Select nutrients in the ovine uterine lumen: IV. Expression of neutral and acidic amino acid transporters in ovine uteri and peri-implantation conceptuses. Biol. Reprod. 80: 1196-1208.

Gao, H.J., G. Wu, T.E. Spencer, G.A. Johnson, and F.W. Bazer. 2009. Select nutrients in the ovine uterine lumen: V. Nitric oxide synthase, GTP cyclohydrolase and ornithine decarboxylase in ovine uteri and peri-implantation conceptuses. Biol. Reprod. 81:67-76.

Gao, H.J., G. Wu, T.E. Spencer, G.A. Johnson, and F.W. Bazer. 2009. Select nutrients in the ovine uterine lumen: VI. Expression of FK506-binding protein 12-rapamycin complex-associated protein 1 (FRAP1) and associated regulators and effectors of mTORC1 and mTORC2 complexes in ovine uteri and peri-implantation conceptuses. Biol. Reprod. 81:87-100.

Lassala, A., F.W. Bazer, T.A. Cudd, P. Li, X.L. Li, M.C. Satterfield, T.E. Spencer, and G. Wu. 2009. Intravenous administration of L-citrulline to pregnant ewes is more effective than L-arginine for increasing arginine availability in the fetus. J. Nutr. 139:660-665.

Lassala, A., F.W. Bazer, T.A. Cudd, S. Datta, D.H. Keisler, M.C. Satterfield, T.E. Spencer, and G. Wu. 2010. Parenteral administration of L-arginine prevents fetal growth restriction in undernourished ewes. J. Nutr. 140:1242-1248.

Lassala, A., F.W. Bazer, T.A. Cudd, S. Datta, D.H. Keisler, M.C. Satterfield, T.E. Spencer, and G. Wu. 2011. Parenteral administration of L-arginine enhances fetal survival and growth in sheep carrying multiple pregnancies. J. Nutr. 141:849-855.

Satterfield, M.C., F.W. Bazer, T.E. Spencer, and G. Wu. 2010. Sildenafil citrate treatment enhances amino acid availability in the conceptus and fetal growth in an ovine model of intrauterine growth restriction. J. Nutr. 140:251-258.

Satterfield, M.C., H.J. Gao, X.L. Li, G. Wu, G.A. Johnson, T.E. Spencer, and F.W. Bazer. 2010. Select nutrients and their associated transporters are increased in the ovine uterus following early progesterone administration. Biol. Reprod. 82:224-231.

Satterfield, M.C. and G. Wu. 2011. Growth and development of brown adipose tissue: significance and nutritional regulation. Front. Biosci. 16:1589-1608.

Kim, J.Y., R.C. Burghardt, G. Wu, G.A. Johnson, T.E. Spencer, and F.W. Bazer. 2011. Select nutrients in the ovine uterine lumen: VII. Effects of arginine, leucine, glutamine, and glucose on trophectodem cell signaling, proliferation, and migration. Biol. Reprod. 84:62-69.

Kim, J.Y., R.C. Burghardt, G. Wu, G.A. Johnson, T.E. Spencer, and F.W. Bazer. 2011. Select nutrients in the ovine uterine lumen: VIII. Arginine stimulates proliferation of ovine trophectoderm cells through mTOR-RPS6K-RPS6 signaling cascade and synthesis of nitric oxide and polyamines. Biol. Reprod. 84:70-78.

Kim, J.Y., R.C. Burghardt, G. Wu, G.A. Johnson, T.E. Spencer, and F.W. Bazer. 2011. Select nutrients in the ovine uterine lumen: IX. Differential effects of arginine, leucine, glutamine and glucose on interferon tau, orinithine decarboxylase and nitric oxide synthase in the ovine conceptus. Biol. Reprod. 84:1139-1147.

Lekatz, L.A., G. Wu, J.S. Caton, J.B. Taylor, L.P. Reynolds, D.A. Redmer, and K.A. Vonnahme. 2011. Maternal selenium supplementation and timing of nutrient restriction in pregnant sheep: Impacts on nutrient availability to the fetus. J. Anim. Sci. 89:59-76.

Swine

Wu, G. 1993. Determination of proline by reversed-phase high performance liquid chromatography with automated pre-column o-phthaldialdehyde derivatization. J. Chromatogr. 641:168-17

Wu, G., and C.J. Meininger. 1993. Regulation of L-arginine synthesis from L-citrulline by L-glutamine in endothelial cells. Am. J. Physiol. 265:H1965-H1971.

Wu, G., and D.A. Knabe. 1994. Free and protein-bound amino acids in sow’s colostrum and milk. J. Nutr. 124:415-424.

Wu, G., D.A. Knabe, and N.E. Flynn. 1994. Synthesis of citrulline from glutamine in pig enterocytes. Biochem. J. 299: 115-121.

Wu, G., A.G. Borbolla, and D.A. Knabe. 1994. The uptake of glutamine and release of arginine, citrulline and proline by the small intestine of developing pigs. J. Nutr. 124:2437-2444.

Dugan, M.E.R., D.A. Knabe, and G. Wu. 1994. Glutamine and glucose metabolism in intraepithelial lymphocytes from pre- and post-weaning pigs. Comp. Biochem. Physiol. 109B:675-681.

Wu, G., D.A. Knabe, W. Yan, and N.E. Flynn. 1995. Glutamine and glucose metabolism in enterocytes of the neonatal pig. Am. J. Physiol. 268:R334-R342.

Wu, G., and N.E. Flynn. 1995. Regulation of glutamine and glucose metabolism by cell volume in lymphocytes and macrophages. Biochim. Biophys. Acta 1243:343-350.

Dugan, M.E.R., D.A. Knabe, and G. Wu. 1995. The induction of citrulline synthesis from glutamine in enterocytes of weaned pigs is not due primarily to age or change in diet. J. Nutr. 125:2388-2393.

Wu, G., and N.E. Flynn. 1995. Effect of HCO3- on glutamine and glucose metabolism in lymphocytes. Metabolism 44:1247-1252.

Wu, G., and D.A. Knabe. 1995. Arginine synthesis in enterocytes of neonatal pigs. Am. J. Physiol. 269:R621-R629.

Wu, G., F.W. Bazer, and W. Tuo. 1995. Developmental changes of free amino acid concentrations in fetal fluids of pigs. J. Nutr. 125:2859-2868.

Wu, G. 1995. Urea synthesis in enterocytes of developing pigs. Biochem. J. 312:717-723.

Wu, G., F.W. Bazer, W. Tuo, and S.P. Flynn. 1996. Unusual abundance of arginine and ornithine in porcine allantoic fluid. Biol. Reprod. 54:1261-1265.

Wu, G. 1996. Effects of concanavalin A and phorbol myristate acetate on glutamine metabolism and proliferation of porcine intraepithelial lymphocytes. Comp. Biochem. Physiol. 114A:363-368.

Flynn, N.E., and G. Wu. 1996. An important role for endogenous synthesis of arginine in maintaining arginine homeostasis in neonatal pigs. Am. J. Physiol. 271:R1149-R1155.

Wu, G., S.A. Meier, and D.A. Knabe. 1996. Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs. J. Nutr. 126:2578-2584.

Wu, G., D.A. Knabe, N.E. Flynn, W. Yan, and S.P. Flynn. 1996. Arginine degradation in developing porcine enterocytes. Am. J. Physiol. 271:G913-G919.

Wu, G. 1996. An important role for pentose cycle in the synthesis of citrulline and proline from glutamine in porcine enterocytes. Arch. Biochem. Biophys. 336:224-230.

Flynn, N.E., and G. Wu. 1997. Enhanced metabolism of arginine and glutamine in enterocytes of cortisol-treated pigs. Am. J. Physiol. 272:G474-G480.

Flynn, N.E., and G. Wu. 1997. Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs. J. Nutr. 127:732-737.

Wu, G. 1997. Synthesis of citrulline and arginine from proline in enterocytes of postnatal pigs. Am. J. Physiol. 272:G1382-G1390.

Wu, G., P.K. Davis, N.E. Flynn, D.A. Knabe, and J.T. Davidson. 1997. Endogenous synthesis of arginine plays an important role in maintaining arginine homeostasis in postweaning growing pigs. J. Nutr. 127:2342-2349.

Wu, G., W.G. Pond, T.L. Ott, and F.W. Bazer. 1998. Maternal dietary protein deficiency decreases amino acid concentrations in fetal plasma and allantoic fluid of pigs. J. Nutr. 128:894-902.

Davis, P.K., and G. Wu. 1998. Compartmentation and kinetics of urea cycle enzymes in porcine enterocytes. Comp. Biochem. Physiol. B 119:527-537.

Wu, G. 1998. Intestinal mucosal amino acid catabolism. J. Nutr. 128:1249-1252.

Wu, G., and S.M. Morris, Jr. 1998. Arginine metabolism: nitric oxide and beyond. Biochem. J. 336:1-17.

Wu, G., W.G. Pond, S.P. Flynn, T.L. Ott, and F.W. Bazer. 1998. Maternal dietary protein deficiency decreases nitric oxide synthase and ornithine decarboxylase activities in placenta and endometrium of pigs during early gestation. J. Nutr. 128:2395-2402.

Flynn, N.E., C.J. Meininger, K. Kelly, N.H. Ing, S.M. Morris, Jr., and G. Wu. 1999. Glucocorticoids mediate the enhanced expression of intestinal type II arginase and argininosuccinate synthase in postweaning pigs. J. Nutr. 129:799-803.

Dillon, E.L., D.A. Knabe, and G. Wu. 1999. Lactate inhibits citrulline and arginine synthesis from proline in pig enterocytes. Am. J. Physiol. 276:G1079-G1086.

Wu, G., T.L. Ott, D.A. Knabe, and F.W. Bazer. 1999. Amino acid composition of the fetal pig. J. Nutr. 129:1031-1038.

Wu, G., C.J. Meininger, D.A. Knabe, F.W. Bazer, and J.M. Rhoads. 2000. Arginine nutrition in development, health and disease. Curr. Opin. Clin. Nutr. Metab. Care 3:59-66.

Wu, G., N.E. Flynn, and D.A. Knabe. 2000. Enhanced intestinal synthesis of polyamines from proline in cortisol-treated piglets. Am. J. Physiol. 279:E395-E402.

Wu, G., C.J. Meininger, K. Kelly, M. Watford, and S.M. Morris, Jr. 2000. A cortisol surge mediates the enhanced expression of pig intestinal pyrroline-5-carboxylate synthase during weaning. J. Nutr. 130:1914-1919.

Wu, G., N.E. Flynn, D.A. Knabe, and L.A. Jaeger. 2000. A cortisol surge mediates the enhanced polyamine synthesis in porcine enterocytes during weaning. Am. J. Physiol. 279:R554-R559.

Flynn, N.E., D.A. Knabe, B.K. Mallick, and G. Wu. 2000. Postnatal changes of plasma amino acids in suckling pigs. J. Anim. Sci.78:2369-2375.

Li, H., C.J. Meininger, and G. Wu. 2000. Rapid determination of nitrite by reversed-phase high-performance liquid chromatography with fluorescence detection. J. Chromatogr. B 746:199-207.

Wu, G., T.E. Haynes, H. Li, and C.J. Meininger. 2000. Glutamine metabolism in endothelial cells: ornithine synthesis from glutamine via pyrroline-5-carboxylate synthase. Comp. Biochem. Physiol. A 126:115-123.

Wu, G., and C.J. Meininger. 2000. Arginine nutrition and cardiovascular function. J. Nutr. 130:2626-2629.

Kepka-Lenhart, D., S.K. Mistry, G. Wu, and S.M. Morris, Jr. 2000. Arginase I: a limiting factor for nitric oxide and polyamine synthesis by activated macrophages? Am. J. Physiol. 279:R2237-R2242.

Meininger, C.J., K.A. Kelly, H. Li, T.E. Haynes, and G. Wu. 2000. Glucosamine inhibits inducible nitric oxide synthesis. Biochem. Biophys. Res. Commun. 279:234-239.

Wu, G., T.E. Haynes, H. Li, W. Yan, and C.J. Meininger. 2001. Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesis. Biochem. J. 353:245-252.

Li, H., C.J. Meininger, J.R. Hawker, Jr., T.E. Haynes, D. Kepka-Lenhart, S.K. Mistry, S.M. Morris, Jr., and G. Wu. 2001. Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells. Am. J. Physiol. 280:E75-E82.

Wu, G., T.E. Haynes, W. Yan, and C.J. Meininger. 2001. Presence of glutamine:fructose-6-phosphate amidotransferase for glucosamine-6-phosphate synthesis in endothelial cells: effects of hyperglycaemia and glutamine. Diabetologia 44:196-202.

Ignarro, L.J., G.M. Buga, L.H. Wei, P.M. Bauer, G. Wu, and P. del Soldato. 2001. Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation. Proc. Natl. Acad. Sci. USA 98:4202-4208.

Marinos, R.S., W. Zhang, G. Wu, K.A. Kelly, and C.J. Meininger. 2001. Tetrahydro-biopterin levels regulate endothelial cell proliferation. Am. J. Physiol. 281:H482-H489.

Dekaney, C.M., G. Wu, and L.A. Jaeger. 2001. Ornithine aminotransferase messenger RNA expression and enzymatic activity in fetal porcine intestine. Pediatr. Res. 50:104-109.

Wei, L.H., G. Wu, S.M. Morris, Jr., and L.J. Ignarro. 2001. Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation. Proc. Natl. Acad. Sci. USA 98:9260-9264.

Singh, R., S. Pervin, G. Wu, and G. Chaudhuri. 2001. Activation of caspae-3 activity and apoptosis in MDA-MB-468 cells by N-hydroxy-L-arginine, an inhibitor of arginase, is not solely dependent on reduction in intracellular polyamines. Carcinogenesis 22:1863-1869.

Meininger, C.J., and G. Wu. 2002. Regulation of endothelial cell proliferation by nitric oxide. Methods Enzymol. 352:280-295.

Li, H., C.J. Meininger, J.R. Hawker, Jr., K.A. Kelly, S.M. Morris, Jr., and G. Wu. 2002. Activities of arginase I and II are limiting for endothelial cell proliferation. Am. J. Physiol. 282:R64-R69.

O’Quinn, P.R., D.A. Knabe, and G. Wu. 2002. Arginine catabolism in lactating porcine mammary tissue. J. Anim. Sci. 80:467-474.

Bush, J.A., G. Wu, A. Suryawan, H.V. Nguyen, and T.A. Davis. 2002. Somatotropin-induced amino acid conservation in pigs involves differential regulation of liver and gut urea cycle enzyme activity. J. Nutr. 132:59-67.

Wu, G., and C.J. Meininger. 2002. Regulation of nitric oxide synthesis by dietary factors. Annu. Rev. Nutr. 22:61-86.

Fang, Y.Z., S. Yang, and G. Wu. 2002. Free radicals, antioxidants, and nutrition. Nutrition 18:872-879.

Flynn, N.E., C.J. Meininger, T.E. Haynes, and G. Wu. 2002. The metabolic basis of arginine nutrition and pharmacotherapy. Biomed. Pharmacother. 56:427-438.

Ignarro, L.J., M. Sisodia, K. Trinh, S. Bedrood, G. Wu, L.H. Wei, and G.M. Buga. 2002. Nebivolol inhibits vascular smooth cell proliferation by mechanisms involving nitric oxide but not cyclic GMP. Nitric Oxide 7:83-90.

Steinle, J.J., C.J. Meininger, R. Forough, G. Wu, M.H. Wu, and H.J. Granger. 2002. Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway. J. Biol. Chem. 277:43830-43835.

Dekaney, C.M., G. Wu, and L.A. Jaeger. 2003. Gene expression and activity of enzymes in the arginine biosynthetic pathway in porcine fetal small intestine. Pediatr. Res. 53:274-280.

Flynn, N.E., and G. Wu. 2003. Regulation of intestinal amino acid metabolism by glucocorticoids. Recent Res. Devel. Physiol. 1:169-178.

Steinle, J.J., C.J. Meininger, U. Chowdhury, G. Wu, and H.J. Granger. 2003. Role of ephrin B2 in human retinal endothelial cell proliferation and migration. Cell. Signal. 15:1011-1017.

Wu, G., L.A. Jaeger, F.W. Bazer, and J.M. Rhoads. 2004. Arginine deficiency in premature infants: biochemical mechanisms and nutritional implications. J. Nutr. Biochem. 15:442-451.

Wu, G., Y.Z. Fang, S. Yang, J.R. Lupton, and N.D. Turner. 2004. Glutathione metabolism and its implications for health. J. Nutr. 134:489-492.

Rhoads, J.M., W. Chen, J. Gookin, G. Wu, Q. Fu, A.T. Blikslager, R.A. Rippe, R.A. Argenzio, W.G. Cance, E.M. Weaver, and L.H. Romer. 2004. L-Arginine stimulates intestinal cell migration through a focal adhesion kinase-dependent mechanism. Gut 53:514-522.

Kim, S.W. and G. Wu. 2004. Dietary arginine supplementation enhances the growth of milk-fed young pigs. J. Nutr. 134:625-630.

Self, J.T., T.E. Spencer, G.A. Johnson, J. Hu, F.W. Bazer, and G. Wu. 2004. Glutamine synthesis in the developing porcine placenta. Biol. Reprod. 70:1444-1451.

Shi, W., C.J. Meininger, T.E. Haynes, K. Hatakeyama, and G. Wu. 2004. Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells. Cell Biochem. Biophys. 41:415-433.

Saraswathi, V., G. Wu, M. Toborek, and B. Hennig. 2004. Linoleic acid-induced endothelial activation: role of calcium and peroxynitrite signaling. J. Lipid Res. 45:794-804.

Wu, G., D.A. Knabe, and S.W. Kim. 2004. Arginine nutrition in neonatal pigs. J. Nutr. 134:2783S-2390S.

McPherson, R.L., F. Ji, G. Wu, J.R. Blanton Jr., and S.W. Kim. 2004. Growth and compositional changes of fetal tissues in pigs. J. Anim. Sci. 82:2534-2540.

Ji, F., G. Wu, J.R. Blanton Jr., and S.W. Kim. 2005. Changes in weight and composition in various tissues of pregnant gilts and their nutritional implications. J. Anim. Sci. 83:366-375.

Wu, G., F.W. Bazer, J. Hu, G.A. Johnson, and T.E. Spencer. 2005. Polyamine synthesis from proline in the developing porcine placenta. Biol. Reprod. 72:842-850.

Kim, S.W., G. Wu, and D.H. Baker. 2005. Ideal protein and amino acid requirements by gestating and lactating sows. Pig News Inform. 26:89N-99N.

Marliss, E.B., S. Chevalier, R. Gougeon, J.A. Morais, M. Lamarche, O.A.J. Adegoke, and G. Wu. 2006. Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover. Diabetologia 49:351-359.

Fu, W.J., J. Hu, T. Spencer, R. Carroll, and G. Wu. 2006. Statistical models in assessing fold changes of gene expression in real-time RT-PCR experiments. Comput. Biol. Chem. 30:21-26.

Jobgen, W.S., S.K. Fried, W.J. Fu, C.J. Meininger, and G. Wu. 2006. Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates. J. Nutr. Biochem. 17:571-588.

Reynolds, L.P., J.S. Caton, D.A. Redmer, A.T. Grazul-Bilska, K.A. Vonnahme, P.B. Borowicz, J.S. Luther, J.M. Wallace, G. Wu, and T.E. Spencer. 2006. Evidence for altered placental blood flow and vascularity in compromised pregnancies. J. Physiol. 572:51-58.

Rojas, J.D., S.R. Sennoune, D. Maiti, K. Bakunts, M. Reuveni, S.C. Sanka, G.M. Martinez, E.A. Seftor, C.J. Meininger, G. Wu, D.E. Wesson, M.J.C. Hendrix, and R. Martinez-Zaguilan. 2006. Vascuolar type H+-ATPases at the plasma membrane regulate pH and cell migration in microvascular endothelial cells. Am. J. Physiol. 291:H1147-H1157.

Wang, J.J., D.F. Li, L.J. Dangott, and G. Wu. 2006. Proteomics and its role in nutrition research. J. Nutr. 136:1759-1762.

Rhoads, M., G. Wu, and J. Galanko. 2006. Serum citrulline levels in infants with short bowel syndrome. J. Pediatr. 148:848-849.

Jobgen, W.S., S.C. Jobgen, H. Li, C.J. Meininger, and G. Wu. 2007. Analysis of nitrite and nitrate in biological samples using high-performance liquid chromatography. J. Chromatogr. B 851:71-82.

Reid, K.M., A. Tsung, T. Kaizu, G. Jeyabalan, A. Ikeda, L. Shao, G. Wu, N. Murase, and D.A. Geller. 2007. Liver I/R Injury is improved by the arginase inhibitor, N-ω-Hydroxy-Nor-L-arginine (Nor-NOHA). Am. J. Physiol. 292:G512-G517.

Chen, L.X., Y.L. Yin, W.S. Jobgen, S.C. Jobgen, D.A. Knabe, W.X. Hu, and G. Wu. 2007. In vitro oxidation of essential amino acids by intestinal mucosal cells of growing pigs. Livest. Sci. 109:19-23.

Frank, J.W., J. Escobar, H.V. Hguyen, S.C. Jobgen, W.S. Jobgen, T.A. Davis, and G. Wu. 2007. Oral N-carbamylglutamate supplementation increases protein synthesis in skeletal muscle of piglets. J. Nutr. 137:315-319.

Rhoads, J.M., B.A. Corl, R. Harrell, X. Niu, L. Gatlin, O. Phillips, A. Blikslager, A. Moeser, G. Wu, and J. Odle. 2007. Intestinal ribosomal p70s6k signaling is increased in piglet rotavirus enteritis. Am. J. Physiol. 292:G913-G922.

Wu, G., F.W. Bazer, T.A. Cudd, W.S. Jobgen, S.W. Kim, A. Lassala, P. Li, J.H. Matis, C.J. Meininger, and T.E. Spencer. 2007. Pharmacokinetics and safety of arginine supplementation in animals. J. Nutr. 137:1673S-1680S.

Mateo, R.D., G. Wu, F.W. Bazer, J.C. Park, I. Shinzato, and S.W. Kim. 2007. Dietary L-arginine supplementation enhances the reproductive performance of gilts. J. Nutr. 137:652-656.

Li, P., Y.L. Yin, D.F. Li, S.W. Kim, and G. Wu. 2007. Amino acids and immune function. Br. J. Nutr. 98:237-252.

Wang X, S.Y. Qiao, Y.L. Yin, L.Y. Yue, Z.Y. Wang, and G. Wu. 2007. Deficiency or excess of dietary threonine reduces protein synthesis in jejunum and skeletal muscle of young pigs. J. Nutr. 137:1442-1446.

Ou, D.Y., D.F. Li, Y.H. Cao, X.L. Li, J.D. Yin, S.Y. Qiao, and G. Wu. 2007. Dietary supplementation with zinc oxide decreases expression of the stem cell factor in the small intestine of weanling pigs. J. Nutr. Biochem. 18:820-826.

Wu, G., F.W. Bazer, T.A. Davis, L.A. Jaeger, G.A. Johnson, S.W. Kim, D.A. Knabe, C.J. Meininger, T.E. Spencer, and Y.L. Yin. 2007. Important roles for the arginine family of amino acids in swine nutrition and production. Livest. Sci. 112:8-22.

Yang, F., J.J. Wang, X.J Li, T.Y. Ying, S.Y. Qiao, D.F. Li, and G. Wu. 2007. Two-dimensional gel electrophoresis and mass spectrometry analysis of interactions between Lactobacillus Fermentum I5007 and intestinal epithelial cells. Electrophoresis 28:4330-4339.

Wu, G., and C.J. Meininger. 2008. Analysis of citrulline, arginine, and methylarginines using high-performance liquid chromatography. Methods Enzymol. 440:177-189.

Wang, J.J., L.X. Chen, D.F. Li, Y.L. Yin, X.Q Wang, P. Li, L.J. Dangott, W.X. Hu and, G. Wu. 2008. Intrauterine growth restriction affects the proteomes of the small intestine, liver and skeletal muscle in newborn pigs. J. Nutr. 138:60-66.

Dekaney, C.M., G. Wu, Y.L. Yin, and L.A. Jaeger. 2008. Regulation of ornithine aminotransferase gene expression and activity by all-trans retinoic acid in Caco-2 intestinal epithelial cells. J. Nutr. Biochem 19:674-681.

Mateo, R.D., G. Wu, H.K. Moon, J.A. Carroll, and S.W. Kim. 2008. Effects of dietary arginine supplementation during gestation and lactation on the performance of lactating primiparous sows and nursing piglets. J. Anim. Sci. 86:827-835.

Wu, G., F.W. Bazer, S. Datta, H. Gao, G.A. Johnson, A. Lassala, P. Li, M.C. Satterfield, T.E. Spencer. 2008. Intrauterine growth retardation in livestock: Implications, mechanisms and solutions. Archiv Fur Tierzucht-Archives of Animal Breeding 51 (Special Issue 1): 4-10.

Wu, G., F.W. Bazer, S. Datta, G.A. Johnson, P. Li, M.C. Satterfield, and T.E. Spencer. 2008. Proline metabolism in the conceptus: Implications for fetal growth and development. Amino Acids 35:691-702.

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Hou, Y.Q., K. Yao, L. Wang, B.Y. Ding, D.B. Fu, Y.L. Liu, H.L. Zhu, J. Liu, Y.T. Li, P. Kang, Y.L. Yin, and G. Wu. 2011. Effects of α-ketoglutarate on energy status in the intestinal mucosa of weaned piglets chronically challenged with lipopolysaccharide. Br. J. Nutr. doi:10.1017/S0007114511000249.

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He, Q.H., P.P. Ren, X.F. Kong, Y.N. Wu, G. Wu, P. Li, F.H. Hao, H.R. Tang, Y.L. Yin. 2011. Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach. J. Nutr. Biochem. doi.10.1016/j.jnutbio.2010.11.007.

Jiawei Wei, J.W., R.J. Carroll, K.K. Harden, and G. Wu. 2011. Comparisons of treatment means when factors do not interact in two-factorial studies. Amino Acids. doi: 10.1007/s00726-011-0924-0

Xi, P.B., Z.Y. Jiang, Z.L. Dai, X.L. Li, K. Yao, C.T. Zheng, Y.C. Lin, J.J. Wang, and G. Wu. 2011. Regulation of protein turnover by L-glutamine in porcine intestinal epithelial cells. J. Nutr. Biochem. (In press)

Meininger, C.J. and G. Wu. 2011. Tetrahydrobiopterin: Important endothelial mediator independent of endothelial nitric oxide synthase. Hypertension (In press)

Ren, W., Y.L. Yin, G. Liu, X. Yu, Y. Li, G. Yang, T. Li, and G. Wu (2011) Effect of dietary arginine supplementation on reproductive performance of mice with porcine circovirus type 2 infection. Amino Acids. doi: 10.1007/s00726-011-0942-y.

Liu, X.D., X. Wu, Y.L. Yin, Y.Q. Liu, M.M. Geng, H.S. Yang, F. Blachier, and G.Y. Wu. 2011. Effects of dietary L-arginine or N-carbamylglutamate supplementation during late gestation of sows on the miR-15b/16, miR-221/222, VEGFA and eNOS expression in umbilical vein. Amino Acids. doi: 10.1007/s00726-011-0948-5.

Gao, K.G., Z.Y. Jiang, Y.C. Lin, C.T. Zheng, G.L. Zhou, F. Chen, L. Yang, and G. Wu. 2011. Dietary L-arginine supplementation enhances placental growth and reproductive performance in sows. Amino Acids. doi: doi: 10.1007/s00726-011-0960-9.

Kong, X.F., B.E. Tan, Y.L. Yin, H.J. Gao, X.L. Li, L.A. Jaeger, F.W. Bazer, and G. Wu. 2011. L-Arginine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. J. Nutr. Biochem. (In press)

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